The World Psoriasis Day
World Psoriasis Day Oct.29th.2022
Gathering our strengths together, working together for a better future
Psoriasis, commonly known as "psoriasis", is a chronic, relapsing, inflammatory, systemic skin disease characterized by a combination of genetics and the environment. In addition to skin manifestations, psoriasis can be accompanied by multi-system diseases such as cardiovascular, metabolic, digestive and malignant tumors. Although it is not contagious, it mainly affects the skin and has a great impact on appearance, which brings a great physical and psychological burden to patients and seriously affects the quality of life. Today is World Psoriasis Day, let us use scientific knowledge to face psoriasis and promote the society's care and attention to psoriasis patients.
Kernel Medical invited theProfessor Li Fuqiu from the Second Hospital of Jilin University authoritatively sharing with us the "Ultraviolet phototherapy in the terminal application of psoriasis treatment".
Key knowledge:
①Routine treatment of psoriasis:
Topical drugs are the first-line treatment for mild-to-moderate psoriasis. The selection of topical drugs and their treatment regimens is based on the patient's age, medical history, type and course of psoriasis, and skin lesions. Commonly used drugs are glucocorticoids, vitamin D3 derivatives, vitamin A acids and so on. Systemic use of methotrexate, cyclosporine, and tretinoin is recommended for patients with scalp psoriasis accompanied by moderate to severe skin lesions throughout the body
Classes and other conventional oral drugs or biological agents.
②Characteristics of UV phototherapy:
A. Phototherapy is the first-line treatment for psoriasis. It mainly induces apoptosis of T cells in psoriatic skin lesions, thereby inhibiting the excessively induced BB-UVB (>280~320nm), NB-UVB (311±2nm), Treatments such as PUVA (oral, medicated, and topical).
B. Ultraviolet light treatment of psoriasis, NB-UVB efficacy is better than BB-UVB, slightly weaker than PUVA. However, NB-UVB has high safety and is convenient to use, and is currently the most commonly used ultraviolet treatment in clinical practice.
C. When the skin lesion area is less than 5% of the total body surface area, local ultraviolet treatment is recommended;
D. When the area of skin lesions is greater than 5% of the total body surface area, whole body UV treatment is recommended.
③NB-UVB treatment of psoriasis:
UVB treatment of psoriasis, the main effective band in the range of 308 ~ 312nm. The effective band of NB-UVB (311±2nm) in the treatment of psoriasis is purer than that of BB-UVB (280~320nm), the efficacy is better, close to the efficacy of PUVA, and the erythema reaction caused by the ineffective band is reduced. It has good safety and has not been found to be related to the occurrence of skin cancer. At present, the clinical application is the most popular.
And if you have any problems or questions, just feel free to contact us, Kernel Medical, our website: www.kernelmedint.com
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